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DPPH radicals scavenging

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldose Reductase (1) Amylases (2) Aryl Hydrocarbon Receptor (1) Cholinesterase (ChE) (1) Elastase (1) Ferroptosis (1) Fungal (2) FXR (1) Glucosidase (2) HIV (1) IFNAR (1) Influenza Virus (1) Interleukin Related (1) Lipoxygenase (1) Microtubule/Tubulin (1) NF-κB (1) NO Synthase (2) Nucleoside Antimetabolite/Analog (1) Parasite (1) Reactive Oxygen Species (8) TNF Receptor (1) TrxR (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (1) Infection (6) Inflammation/Immunology (32) Metabolic Disease (9) Neurological Disease (4)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Peptides

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3985

Gyrophoric acid	Others	Cancer
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows **DPPH radical scavenging** activity with an IC₅₀ value of 105.75 µg/ml .

HY-W001542

5-Hydroxyoxindole	Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
5-Hydroxyoxindole is a structural analog of uric acid. 5-Hydroxyoxindole has *DPPH* radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .

HY-111523

Isomahanine

Others Metabolic Disease

Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .
HY-N7518

Eulophiol

Others Inflammation/Immunology

Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

Isomahanine	Others	Metabolic Disease
Isomahanine, carbazole alkaloid, is an antioxidative agent. Isomahanine has DPPH radical scavenging activity with an IC₅₀ value of 24 μM .

Eulophiol	Others	Inflammation/Immunology
Eulophiol shows the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity with an EC₅₀ of 27.7μM. Antioxidant activity .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Others	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-N10927

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene	Others	Others
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC₅₀ value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity .

HY-146172

Antioxidant agent-3	Reactive Oxygen Species	Inflammation/Immunology Cancer
Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent **DPPH radicals scavenging** activity and ABTS ⁺ scavenging activity with IC₅₀s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H₂O₂-treated HepG2 cells .

HY-111898

Epirosmanol	Others	Cancer
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .

HY-121153

Altenusin

Alutenusin
FXR Others

Altenusin shows markedly DPPH radical scavenging activities.

Altenusin Alutenusin	FXR	Others
Altenusin shows markedly DPPH radical scavenging activities.

HY-N9814

Shanciol B	NO Synthase	Inflammation/Immunology
Shanciol B, isolated from the ethyl acetate extract of the air-dried whole plant of Pholidota imbricate Hook, inhibits nitric oxide (NO) production and 1,1-diphenyl-2-picrylhydrazil (DPPH) radical scavenging activity . Shanciol B is a microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor with anti-inflammatory activity .

HY-133183

Urolignoside	Others	Others
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model .

HY-155346

Free radical scavenger 1

Others Others

Free radical scavenger 1 (compound 8) shows scavenging activity against the DPPH radical, with the IC₅₀ of 43.39 μg/ml .
HY-N3141

Olivil

(-)-Olivile; Vladinol C
Others Others

Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC₅₀: 176 μM) .
HY-W018643A

(E)-Ferulic acid methyl ester

Methyl (E)-ferulate
Others Others

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

Free radical scavenger 1	Others	Others
Free radical scavenger 1 (compound 8) shows scavenging activity against the *DPPH* radical, with the IC₅₀ of 43.39 μg/ml .

Olivil (-)-Olivile; Vladinol C	Others	Others
Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC₅₀: 176 μM) .

(E)-Ferulic acid methyl ester Methyl (E)-ferulate	Others	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N9447

Norbergenin 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC₅₀ 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .

HY-N3858

Erythristemine	Others	Inflammation/Immunology
Erythristemine is an alkaloid that can be isolated from Erythrina lysistemon. Erythristemine has weak DPPH radical scavenging properties .

HY-N6043

Hydroxytyrosol acetate	Others	Inflammation/Immunology
Hydroxytyrosol acetate is found in the olive oil with an antioxidant activity. Hydroxytyrosol acetate had a weaker DPPH radical scavenging activity than hydroxytyrosol .

HY-N11895

Isorabaichromone	Reactive Oxygen Species	Inflammation/Immunology
Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .

HY-N6672

Caulophylline B	Others	Inflammation/Immunology
Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical .

HY-N7931

Regaloside A 1 Publications Verification	NO Synthase NF-κB	Inflammation/Immunology
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .

HY-N10770

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone	Others	Metabolic Disease
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .

HY-N8579

Eugenyl benzoate	Others	Inflammation/Immunology
Eugenyl benzoate has the potency for scavenging of DPPH radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors .

HY-N3349A

(-)-Lyoniresinol	Others	Others
(-)-Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. (-)-Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-N3349

Lyoniresinol	Others	Others
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC₅₀ of 82.4 μM .

HY-112053

DPPH Maximum Cited Publications 11 Publications Verification 2,2-Diphenyl-1-picrylhydrazyl	Others	Metabolic Disease
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .

HY-N8169

10-O-Trans-p-methoxycinnamoylcatalpol	Others	Others
10-O-Trans-p-methoxycinnamoylcatalpol has antioxidant activity with the IC₅₀ value of 0.37 μM/mL in DPPH free radical scavenging assay .

HY-N4111

Wushanicaritin	Others	Inflammation/Immunology Cancer
Wushanicaritin exhibits significant antioxidant activity (IC₅₀=35.3 μM) in DPPH radical scavenging activity tests. Antitumor effects and anti-inflammatory property .

HY-N11469

Cyclobisdemethoxycurcumin	Others	Others
Cyclobisdemethoxycurcumin is an antioxidant agent with IC₅₀s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .

HY-121811

Pongamol Lanceolatin C	Glucosidase	Metabolic Disease Inflammation/Immunology
Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC₅₀=103.5 μM) and has free-radical (DPPH) scavenging,antihyperglycemic, and antihyperglycemic activities .

HY-N8194

Syringetin-3-O-glucoside Syringetin 3-O-β-D-glucoside	Others	Neurological Disease
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .

HY-130294

Pyracrenic acid	Elastase	Inflammation/Immunology
Pyracrenic acid is an elastase inhibitor (IC₅₀ = 2.42 µM), can be obtained from the bark of Pyracantha crenulata. Pyracrenic acid has DPPH free radical scavenging activity and anti-inflammatory activity .

HY-N10020

Patulitrin	Lipoxygenase	Inflammation/Immunology
Patulitrin has scavenging effect in the DPPH radical. Patulitrin inhibits soybean lipoxygenase. Patulitrin also has antihypertensive effect. Patulitrin is an antioxidant flavonoid that can be isolated from Anthemis tinctoria .

HY-W274194

Antioxidant agent-7	Others	Others
Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC₅₀ value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .

HY-N1417

Sesamol 1 Publications Verification
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC₅₀=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .

HY-N8254

Haginin A	Others	Others
Haginin A (compound 3）can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC₅₀ *values of 9.0 μM and 37.7 μM in the ABTS system and DPPH* system, respectively .**

HY-131803

3'-Azido-3'-deoxyguanosine	Nucleoside Antimetabolite/Analog	Inflammation/Immunology
Urolignoside is an antioxidant with free radical scavenging activity. Urolignoside potently scavenges DPPH radical, and exhibits antioxidant to β-carotene-lineoleate model . 3'-Azido-3'-deoxyguanosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-N9895

3,5-Dicaffeoyl-epi-quinic acid	Others	Infection Inflammation/Immunology
3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge *DPPH* radical and superoxide anion radical, with IC₅₀s of 5.6 and 2.9 μg/mL respectively .

HY-W714006

Cochliodinol	Others	Metabolic Disease
Cochliodinol (compound 1) is a metabolite derived from the Apis mellifera ligustica. Cochliodinol has strong free radical scavenging activity of 2, 2-diphenyl-1-picrohydrazine (DPPH) (IC₅₀=3.06 μg/mL) .

HY-N12443

Antioxidant agent-18	Others	Inflammation/Immunology
Antioxidant agent-18 (compound 5) is a flavonol glycoside with antioxidant activity isolated from Ginkgo biloba. Antioxidant agent-18 scavenges DPPH radicals (IC₅₀: 15.8 μM) and reduces cytochrome c (IC₅₀: 14.7 μM).

HY-N1994

Swertianine
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .

HY-N10294

Epicoccone B	HIV	Infection Inflammation/Immunology
Epicoccone B, firstly reported from C. globosum, exhibits the DPPH free radical scavenging ability with IC₅₀ value of 10.8 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 27.3 μM. Anti-HIV activity .

HY-N10742

Maritimetin	Reactive Oxygen Species	Cardiovascular Disease
Maritimein is an aurone that can be isolated from Coreopsis tinctoria. Maritimein shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with an IC₅₀ value of 4.12 μM. Maritimein can be used for the research of cardiovascular disease .

HY-156711

Ternatumoside II	Others	Inflammation/Immunology
Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC₅₀s: 260.5 μM and 320.2 μM for DPPH and ABTS) .

HY-N5130

Effusol	Others	Neurological Disease
Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC₅₀ values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline .

HY-N0539

Calceolarioside B	Aldose Reductase	Cancer
Calceolarioside B is a natural product isolated from Akebia quinata leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC₅₀ of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC₅₀ of 94.60 μM .

HY-136593

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (S)-3-(4-Hydroxyphenyl)lactic acid	Others	Others
(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid (compound 1) is a metabolite isolated from the culture medium of Leuconostoc mesenteroides. (S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid has high DPPH radical-scavenging activities and antioxidative activities .

HY-N7648

Atherosperminine Atherospermine	Parasite	Infection
Atherosperminine（Atherospermine）is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC₅₀ of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical *DPPH, with an IC₅₀* of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis .

HY-N3421

Koaburaside	Interleukin Related TNF Receptor Influenza Virus	Infection Inflammation/Immunology Cancer
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

HY-149313

α‑Amylase-IN-1	Amylases	Metabolic Disease
α Amylase-IN-1 (Compound 11) is an α-Amylase inhibitor with an IC₅₀ value of 0.5509 μM. α Amylase-IN-1 has antioxidant activity with an IC₅₀ value of 53.49 μM for scavenging *DPPH* free radicals. IC₅₀ can be used in the study of diabetes and oxidative stress-related diseases.

HY-N9953

Chrysophanol 8-O-β-D-(6′-O-galloyl)glucopyranoside	Others	Inflammation/Immunology
Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside, an anthraquinone glucoside, can be isolated from Rheum undulatum L. Chrysophanol 8-O-β-D-(6’-O-galloyl)glucopyranoside has potent DPPH radical and ?O₂ ^- scavenging activity .

Cat. No.	Product Name	Target	Research Area

HY-P5316

MHLWAAK	Peptides	Inflammation/Immunology
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317

MAQAAEYYR	Peptides	Inflammation/Immunology
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH and ABTS radical scavenging ability. MAQAAEYYR protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318

MDYYFEER	Peptides	Inflammation/Immunology
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5316A

MHLWAAK TFA	Peptides	Inflammation/Immunology
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5317A

MAQAAEYYR TFA	Peptides	Inflammation/Immunology
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH and ABTS radical scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P5318A

MDYYFEER TFA	Peptides	Inflammation/Immunology
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H₂O₂-induced oxidative damage .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

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DPPH radicals scavenging

Inhibitors & Agonists

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